2018-09-20

23 Jan 2019 The company that developed NARCAN® Nasal Spray is Opiant “Nalmefene is another opioid antagonist and similar to naloxone,” Crystal 31 Mar 2021 Opiant Pharmaceuticals Announces Final Tranche of NIDA Grant Award of OPNT003, nasal nalmefene, for the treatment of opioid overdose. evaluation of an intranasal formulation of nalmefene, a long acting opioid antagonist (t1/2 ~ 10.8 h). Recipient Name: OPIANT PHARMACEUTICALS, INC. 21 Sep 2018 of opioid antagonist nalmefene, as a defense against hostile use of the drug. The BARDA contract could be worth up to $4.6 million. Opiant 11 Apr 2018 Opiant announces development of intranasal nalmefene for treatment of opioid overdose.

Opiant nalmefene

OPNT003, nasal nalmefene, is in development as a potent, rapid-onset, long-acting opioid antagonist for the treatment of opioid overdose. OPNT003 is designed as a rescue medication that could be especially useful in treating overdose by high-potency synthetic opioids, such as fentanyl. Study Drugs. Nalmefene hydrochloride (cGMP grade) was purchased from Rusan PharmaLtd.

OPNT003 is designed as a rescue medication that could be Opiant Pharmaceuticals Inc (NASDAQ: OPNT) has dosed the first subjects in a head-to-head clinical study comparing the effectiveness of its investigational opioid antagonist nasal nalmefene “The initiation of this head-to-head study is an important step in our comprehensive development program for OPNT003, nasal nalmefene,” said Dr. Roger Crystal, President and CEO, Opiant “The initiation of this head-to-head study is an important step in our comprehensive development program for OPNT003, nasal nalmefene,” said Dr. Roger Crystal, President and CEO, Opiant Pharmaceuticals. “The potential for a faster acting, longer duration antagonist holds promise in the fight against an increasing number of opioid An intranasal formulation of nalmefene, a long-lasting opioid antagonist, designated as OPNT 003, is under development by Opiant Pharmaceuticals, for the For the fourth quarter of 2020, Opiant reported revenue of $10.0 million, including $8.3 million of revenue from the licensing agreement with Adapt Pharma Operations Limited, a subsidiary of

Opiant is a specialty pharmaceutical company developing pharmacological treatments for addictions and drug overdose and is working with Consort Medical to develop a delivery device for its OPNT003 (intranasal nalmefene), a long-lasting opioid antagonist for the treatment of opioid overdose.

Opiant Pharmaceuticals Announces First Patient Dosed in Confirmatory Pharmacokinetic Study Assessing OPNT003, Nasal Nalmefene, for the Treatment of Pharmacodynamic study will compare OPNT003, nasal nalmefene, with nasal naloxone in reversing the respiratory depression produced by the synthetic opioid, TradingView UK. View live OPIANT PHARMACEUTICALS INC chart to track its stock's price action. Find market predictions, OPNT financials and market news. Opiant Pharmaceuticals, Inc.March 31, 2021 of Health (“NIH”), to support the development of OPNT003, nasal nalmefene, for the treatment of opioid overdose. 22 Feb 2019 A phase 2 trial of Opiant Pharmaceuticals' naloxone nasal spray nasal nalmefene for opioid overdose, preparing to enroll patients into a 31 Mar 2021 Read Press Release for Opiant Pharmaceuticals (OPNT) published on of OPNT003, nasal nalmefene, for the treatment of opioid overdose.

“The initiation of this head-to-head study is an important step in our comprehensive development program for OPNT003, nasal nalmefene,” said Dr. Roger Crystal, President and CEO, Opiant

SANTA MONICA, Calif., Oct. 29, 2020 (GLOBE NEWSWIRE) -- Opiant Pharmaceuticals, Inc. (“Opiant”) (NASDAQ: OPNT Opiant Pharmaceuticals Announces First Patient Dosed in Confirmatory Pharmacokinetic Study Assessing OPNT003, Nasal Nalmefene, for the Treatment of Opioid Overdose 2021-02-08 · Opiant Pharmaceuticals Announces First Patient Dosed in Confirmatory Pharmacokinetic Study Assessing OPNT003, Nasal Nalmefene, for the Treatment of Opioid Overdose SANTA MONICA, Calif., Feb. 08 Opiant Pharmaceuticals Inc (NASDAQ: OPNT) has dosed the first subjects in a head-to-head clinical study comparing the effectiveness of its investigational opioid antagonist nasal nalmefene 2021-04-05 · Opiant Pharmaceuticals Announces First Subjects Dosed in Study Comparing OPNT003, Nasal Nalmefene, With Nasal Naloxone PRESS RELEASE GlobeNewswire Apr. 5, 2021, 10:01 PM Opiant Pharmaceuticals, Inc. (“Opiant”) (NASDAQ: OPNT) today announced it has entered into an agreement with drug delivery specialist Aptar Pharma (“Aptar”), for the development of OPNT003 nasal nalmefene for use in conjunction with Aptar’s Unit Dose System (UDS) for the treatment of opioid overdose. SANTA MONICA, Calif., April 05, 2021 (GLOBE NEWSWIRE) -- Opiant Pharmaceuticals, Inc. (“Opiant”) (NASDAQ: OPNT), a specialty pharmaceutical company developing medicines to treat addictions and drug overdose, today announced that the first subjects were dosed in a head-to-head clinical study comparing the effectiveness of its investigational opioid antagonist OPNT003, nasal nalmefene, with nasal naloxone. Opiant had previously conducted an initial PK study of IN nalmefene that showed rapid increases in plasma levels with an onset faster than an intramuscular injection along with a long half-life (6 Opiant is a pharmaceutical company with a mission to create best-in-class medicines for the treatment of addictions and drug overdose. We are headquartered in Santa Monica, with additional offices in London, UK. We were founded in 2009. In 2013, Opiant developed the first FDA-approved, user-friendly nasal naloxone spray.

2020-11-02 · Opiant Pharmaceuticals said that it has terminated an agreement for the use of Bespak’s Unidose Xtra device for delivery of its OPNT003 intranasal nalmefene for the treatment of opioid overdose and has entered into a new agreement with Aptar Pharma for the use Aptar’s Unit Dose System (UDS) to deliver OPNT003.
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15 Dec 2020 On December 10, 2020, Opiant Pharmaceuticals, Inc., a specialty nasal nalmefene, an investigational treatment for opioid overdose, which 20 Sep 2018 As part of Consort's deal, its units Aesica and Bespak will work with Opiant to produce a clinically pre-filled nasal spray with nalmefene. 10 Dec 2020 Opiant plans to use the proceeds to fund the potential future commercialization of OPNT003, nasal nalmefene, an investigational treatment for Co.'s principal products include OPNT002 - Nasal Naltrexone for Alcohol Use Disorder; OPNT003 - Intranasal Nalmefene for Opioid Overdose Reversal; and 9 May 2018 Opiant Pharmaceuticals (NASDAQ:OPNT), a specialty pharmaceutical ( intranasal nalmefene), a long acting treatment for opioid overdose. 2 Jan 2020 More companies could investigate the efficacy of using the drug nalmefene (used primarily in the management of alcohol dependence) as 13 Mar 2018 Just as Opiant Pharmaceuticals did with naloxone, the company has turned to an old drug that was once available as an injection – nalmefene.

The IN and intramuscular solutionswereformulatedbytheVince&AssociatesClinicalResearch (VACR) pharmacy staff.
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nalmefene solution in one nostril). Treatment D: 1.5 mg i.m. (1.5 ml of a 1.0-mg/ml nalmefene solution). The IN treatments were randomized while the intramuscular dose was the last treatment of all subjects. The high dose (3 mg) of nalmefene was selected based on the relative bioavailability (∼50%)

The Aptar UDS has been approved by the U.S. Food and Drug Administration (FDA 2020-10-30 Agreement combines Opiant’s opioid antagonist OPNT003 nasal nalmefene, with Aptar's FDA-approved Unit Dose System delivery device; Reinforces Opiant’s continued commitment to innovative overdose treatment options as America’s opioid epidemic worsens ; OPNT003 nasal nalmefene remains on track for NDA submission by the end of 2021; SANTA MONICA, Calif., Oct. 29, 2020 (GLOBE NEWSWIRE Agreement combines Opiant’s opioid antagonist OPNT003 nasal nalmefene, with Apta r's FDA-approved Unit Dose System delivery device; Reinforces Opiant’s continued commitment to innovative overdose treatment options as America’s opioid epidemic worsens ; OPNT003 nasal nalmefene remains on track for NDA submission by the end of 2021; SANTA MONICA, Calif., Oct. 29, 2020 (GLOBE NEWSWIRE “We thank BARDA for their ongoing support of OPNT003, nasal nalmefene,” said Roger Crystal, M.D., President and Chief Executive Officer of Opiant. “We believe OPNT003, nasal nalmefene, has the potential to be a best-in-class rescue agent for preventing opioid overdose deaths, particularly from synthetic opioids like fentanyl. Opiant Pharmaceuticals, Inc. (NASDAQ:OPNT) Q1 2020 Earnings Conference Call May 12, 2020 4:30 PM ET Company Participants Ben Atkins – Vice President of Communication and Investor Relations 2021-02-08 * Agreement combines Opiant’s opioid antagonist OPNT003 nasal nalmefene, with Aptar's FDA-approved Unit Dose System delivery device * Reinforces Opiant’s continued commitment to innovative overdose treatment options as America’s opioid epidemic worsens * OPNT003 nasal nalmefene remains on track for NDA submission by the end of 2021 SANTA MONICA, Calif., Oct. 29, 2020 (GLOBE NEWSWIRE We have responded to this call, and are developing an intranasal formulation of nalmefene, a more potent, longer acting opioid antagonist that is especially well-suited to treat overdose caused by synthetics.

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Opiant is a pharmaceutical company with a mission to create best-in-class medicines for the treatment of addictions and drug overdose. We are headquartered in Santa Monica, with additional offices in London, UK. We were founded in 2009. In 2013, Opiant developed the …

(Mumbai, India). The IN and intramuscular solutionswereformulatedbytheVince&AssociatesClinicalResearch (VACR) pharmacy staff. Nalmefene was dissolved in 0.1 M citrate buffer, pH 4.0, for all IN formulations.